The Hepato pancreato biliary disease is referred to any condition that affects the health of our liver, pancreas, gallbladder, and the biliary duct. Where few patients might get diagnosed with the disease as a hereditary or genetic defect, there are few very common symptoms to look for such as, jaundice, darker urine color, and lighter stool color and can occur due to chronic damage to the tissues and organs involved.


Following are the common causes of Hepato Pancreato biliary cancer :

  1. Liver disease :
    • Chronic hepatitis infections
    • Scarring of the liver that prevents the organs from functioning well
    • Excessive alcohol consumption (alcoholic hepatitis)
    • Infectious disease of the liver
    • Inflammatory conditions (sarcoidosis, abscess, and non-alcoholic steatohepatitis)
    • End-stage liver damage
    • Formation of cysts in the liver
    • Liver infarction, peliosis hepatitis,
    • Metabolic disease
  2. Biliary Disease :
    • Gallstones
    • Gallbladder Cancer
    • Bile duct cancer
    • Inflammation of the bile duct
    • Inflammation of the gallbladder
  3. Pancreatic disease :
    • Chronic alcoholism
    • Family history in this disease
    • Inflammation in the pancreas


  • Jaundice
  • Abdominal pain and swelling
  • Itchy skin
  • Blood in the stool
  • Legs and ankle swelling
  • Vomiting and Nausea
  • Loss of appetite

Treatment Overview

Patients suffering from Hepato-pancreato-biliary diseases should first consult the hepatologist. Depending on the severity and stage of the disease, your doctor would recommend a hepatobiliary surgeon. The surgeon will then examine the case and start with one of the various treatment options such as cholecystectomy (gallbladder and biliary disease), internal radiation therapy, and so on. Contact our expert SaiShree team to get into more details regarding the treatment options for this complex disease.